Lab test
Total Glutathione Test
This page explains the total glutathione test, what it measures, and how to order it. This test measures the total amount of glutathione in your body. Glutathione is an important antioxidant.
What this test is
Total Glutathione is a measure of the sum of reduced glutathione (GSH) and oxidized glutathione (GSSG) in the blood. GSH is the most abundant intracellular antioxidant, playing a crucial role in protecting cells from oxidative damage.
What it measures
- Total Glutathione — reflects the sum of reduced and oxidized forms of this key antioxidant
What the test involves
This test requires a blood sample. A healthcare professional will draw blood from a vein in your arm.
Why it is often ordered
Clinicians may order this test to assess a person's overall antioxidant status. It can help evaluate potential oxidative stress or the body's ability to detoxify.
Preparation
You will need to follow specific instructions provided by the laboratory for sample collection. It is important to adhere to these guidelines for accurate results.
How results are reported
Results are typically available within a few business days and will be sent to you. Reference ranges, which indicate what is considered typical, are established by each laboratory and may vary.
Before you go
- Fasting requirements
- Specific collection time
- Any dietary restrictions
FAQ
Frequently asked questions
What is glutathione?
Glutathione is a molecule naturally produced by the body, acting as a powerful antioxidant. It helps protect cells from damage caused by free radicals and plays a role in detoxification processes.
Why is measuring total glutathione important?
Measuring total glutathione provides an overall picture of the body's antioxidant capacity. Low levels may indicate increased oxidative stress or impaired detoxification, which can be linked to various health concerns.
Can diet affect glutathione levels?
Yes, certain nutrients found in foods like sulfur-rich vegetables (broccoli, garlic), vitamin C, and selenium can support the body's natural production of glutathione. A balanced diet is generally beneficial.
How is total glutathione different from reduced glutathione?
Total glutathione measures both the active (reduced) form and the inactive (oxidized) form. Reduced glutathione (GSH) is the primary active antioxidant, while oxidized glutathione (GSSG) is its byproduct.
Related
Related tests
Locations
Request Total Glutathione Test by state
Choose a state for local context.